exRNAdisease

Entry Detail

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General Information

Database ID: exR0428945 RNA Name: ADM RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 10305073 End Site(bp): 10307397 External Links: ENSG00000148926

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RASIP1 chr19 48720585 48740610 - YWHAG chr7 76326799 76358991 - SCRIB chr8 143790920 143815773 - CARHSP1 chr16 8852942 8869012 - FAU chr11 65120630 65122177 - DOLK chr9 128945530 128947603 - TMEM39B chr1 32072031 32102866 + ATP13A3 chr3 194402672 194498364 - PIEZO1 chr16 88715338 88785220 - MCUB chr4 109560209 109688719 + SSR2 chr1 156009048 156020951 - ARPC3 chr12 110434823 110450422 - PSMC4 chr19 39971165 39981764 + THOC3 chr5 175917873 176034680 - PRELID3B chr20 59033145 59042809 - CBX3 chr7 26201162 26213607 + SNX19 chr11 130875436 130916509 - STAT1 chr2 190908460 191020960 - HSP90AB1 chr6 44246166 44253888 + PSMF1 chr20 1113240 1189415 + COQ10A chr12 56266858 56270966 + SRSF7 chr2 38743599 38751494 - DDIT4 chr10 72273924 72276036 + OSGIN2 chr8 89901849 89927888 + IRS4 chrX 108732482 108736409 - CENPP chr9 92325953 92620529 + LCMT1 chr16 25111731 25178231 + PACS1 chr11 66070272 66244744 + ATP1B3 chr3 141876124 141926549 + EPS15 chr1 51354263 51519266 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-363-3p chrX 134169382 134169403 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-92b-3p chr1 155195237 155195258 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - AC073111.3 chr7 150379329 150410597 + PAUPAR chr11 31812307 32002405 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.