exRNAdisease

Entry Detail

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General Information

Database ID: exR0428947 RNA Name: ADNP RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 50888916 End Site(bp): 50931437 External Links: ENSG00000101126

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HNRNPA3 chr2 177212563 177223958 + GRPEL1 chr4 7058895 7068064 - SNRPA chr19 40750637 40765389 + IL9R chrX 155997581 156010817 + RPLP0 chr12 120196699 120201235 - COG8 chr16 69320140 69339667 - CREBRF chr5 173056352 173139284 + RREB1 chr6 7107597 7251980 + LMO2 chr11 33858576 33892076 - HDGF chr1 156742109 156766925 - TUBA1B chr12 49127782 49131397 - ZFAND3 chr6 37819727 38154624 + CUL9 chr6 43182184 43224587 + SLC39A10 chr2 195575977 195737702 + GATD1 chr11 767220 777488 - POLR2B chr4 56977722 57031158 + HPS5 chr11 18278668 18322198 - KDM3B chr5 138352685 138437028 + CCT3 chr1 156308968 156367873 - ACOT9 chrX 23701055 23766475 - MTCH1 chr6 36968141 36986298 - LRP11 chr6 149818757 149864359 - LMAN1 chr18 59327823 59359265 - EIF4E2 chr2 232550674 232583644 + CBL chr11 119206298 119313926 + ATP5MC3 chr2 175176258 175184607 - C18orf25 chr18 46173553 46266992 + MAP7D1 chr1 36155579 36180849 + HMGA1 chr6 34236873 34246231 + PRMT3 chr11 20387558 20509338 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AJ271736.1 chrX 156004218 156022236 + AC079949.1 chr12 127142029 127146532 - MALAT1 chr11 65497688 65506516 + MIR17HG chr13 91347820 91354579 + TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.