exRNAdisease

Entry Detail

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General Information

Database ID: exR0428948 RNA Name: ADNP2 RNA Type: mRNA Chromosome: chr18 Starnd: + Coordinate: Start Site(bp): 80109262 End Site(bp): 80147523 External Links: ENSG00000101544

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PWP2 chr21 44107373 44131181 + USP14 chr18 158383 214629 + ERBB2 chr17 39687914 39730426 + EEF2 chr19 3976056 3985463 - MT-ND2 chrMT 4470 5511 + RPL26 chr17 8377516 8383213 - TOM1L2 chr17 17843511 17972422 - DSC2 chr18 31058840 31102522 - ARID4B chr1 235131634 235328219 - FBXO42 chr1 16246840 16352480 - PEBP1 chr12 118136124 118145584 + CDC42EP3 chr2 37641882 37738468 - NOMO3 chr16 16232528 16294811 + PTMA chr2 231706895 231713541 + ACTA2 chr10 88935074 88991339 - ACTB chr7 5527148 5563784 - PRKCI chr3 170222424 170305977 + TOMM70 chr3 100363431 100401089 - FP565260.1 chr21 5130871 5154658 - RPS20 chr8 56067295 56074581 - SH3GLB1 chr1 86704570 86748184 + GRID2IP chr7 6497462 6551436 - COL4A2 chr13 110305812 110513209 + PGP chr16 2211593 2214840 - CERS6 chr2 168455862 168775137 + NAP1L1 chr12 76036585 76084958 - ALDOA chr16 30064164 30070457 + RPA2 chr1 27891524 27914746 - ITM2C chr2 230864639 230879248 + CALR chr19 12938578 12944489 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4508 chr15 23562107 23562123 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC135178.2 chr17 8318088 8318712 - AL391294.1 chrX 81000150 81004217 - HOXA-AS2 chr7 27107777 27134302 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.