exRNAdisease

Entry Detail

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General Information

Database ID: exR0428949 RNA Name: ADO RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 62804720 End Site(bp): 62808479 External Links: ENSG00000181915

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand B3GNT10 chr9 120792403 120799918 + PTMA chr2 231706895 231713541 + ANAPC15 chr11 72106378 72112780 - ZNF581 chr19 55635459 55645623 + MTRNR2L12 chr3 96617188 96618236 - RPS11 chr19 49496365 49499708 + UBR5 chr8 102252273 102412759 - TRAPPC4 chr11 119018763 119025454 + NOL11 chr17 67717931 67744531 + GDI2 chr10 5765223 5842132 - GUF1 chr4 44678420 44700928 + XPOT chr12 64404392 64451125 + YWHAQ chr2 9583967 9630997 - E2F5 chr8 85177154 85217158 + RPS17 chr15 82536750 82540459 - MBTD1 chr17 51177425 51260163 - GNAI3 chr1 109548615 109600195 + NEK9 chr14 75079353 75127344 - RPS15 chr19 1438358 1440494 + GRIK2 chr6 101181257 102070083 + PRRC2A chr6 31620715 31637771 + DMTF1 chr7 87152361 87196337 + ERI3 chr1 44221070 44355260 - TSN chr2 121737103 121767853 + ADK chr10 74151202 74709963 + MFGE8 chr15 88898683 88913381 - UBE2G2 chr21 44768580 44801826 - HERPUD2 chr7 35632659 35695571 - CREG1 chr1 167529117 167553805 - HMGA1 chr6 34236873 34246231 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009163.4 chr16 75458252 75460017 - KANSL1-AS1 chr17 46193576 46196723 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.