exRNAdisease

Entry Detail

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General Information

Database ID: exR0428951 RNA Name: ADORA2A RNA Type: mRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 24417879 End Site(bp): 24442357 External Links: ENSG00000128271

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TUBA1A chr12 49184795 49189080 - ILK chr11 6603708 6610874 + RPL23A chr17 28719985 28724359 + TUB chr11 8019244 8106112 + GABARAP chr17 7240008 7242449 - RETREG2 chr2 219176225 219185475 + RPS3 chr11 75399515 75422280 + LMNA chr1 156082573 156140089 + SPECC1L chr22 24270817 24417739 + IFI30 chr19 18173162 18178117 + NFKB2 chr10 102394110 102402524 + RPL9 chr4 39452521 39458949 - MX1 chr21 41420304 41459214 + EIF4B chr12 53006158 53042209 + LRFN4 chr11 66856647 66860475 + CTSH chr15 78921058 78949574 - CHCHD3 chr7 132784870 133082090 - ITGB1 chr10 32900318 33005792 - MTPN chr7 135926760 135977359 - IFFO1 chr12 6538375 6556083 - CLK3 chr15 74598500 74645414 + RPL3 chr22 39312882 39320389 - P4HB chr17 81843161 81860624 - RPS16 chr19 39433137 39435949 - VAMP5 chr2 85584431 85593406 + SPECC1L-ADORA2A chr22 24270898 24442356 + TMSB4X chrX 12975110 12977227 + MCM2 chr3 127598410 127622436 + ACTG1 chr17 81509971 81523847 - EIF3D chr22 36510855 36529184 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL121832.3 chr20 62402236 62405935 - AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.