exRNAdisease

Entry Detail

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General Information

Database ID: exR0428954 RNA Name: ADPGK RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 72751369 End Site(bp): 72785846 External Links: ENSG00000159322

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EEF1A1 chr6 73515750 73523797 - B4GAT1 chr11 66345374 66347629 - MKNK2 chr19 2037465 2051244 - UBA2 chr19 34428352 34471251 + PGK1 chrX 77910739 78129295 + STAMBP chr2 73828916 73873659 + CCDC150 chr2 196639554 196763490 + SRSF1 chr17 58000919 58007346 - GTF3C2 chr2 27325849 27357034 - EIF3H chr8 116642130 116766925 - ACTB chr7 5527148 5563784 - GMCL1 chr2 69829660 69881384 + BCAR3 chr1 93561741 93847150 - UBE2V2 chr8 48008415 48064708 + MTHFD2 chr2 74198610 74217565 + MT-CO1 chrMT 5904 7445 + NOL8 chr9 92297358 92325636 - EFTUD2 chr17 44849948 44899445 - PPP1R14B chr11 64244479 64246943 - ZFP42 chr4 187995771 188005046 + ATG4B chr2 241637213 241673857 + NDUFB3 chr2 201071433 201085750 + BCKDK chr16 31106107 31112791 + PCBP2 chr12 53452102 53481162 + MORC4 chrX 106813871 107000212 - HMGB2 chr4 173331376 173334432 - SLC25A29 chr14 100291116 100306547 - TBCA chr5 77691166 77868780 - SACS chr13 23328826 23433740 - PASK chr2 241106099 241150264 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC135050.1 chr16 31056460 31062803 + AL355488.1 chr1 110370154 110373003 + PCBP2-OT1 chr12 53464468 53465057 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.