exRNAdisease

Entry Detail

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General Information

Database ID: exR0428955 RNA Name: ADPRH RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 119579268 End Site(bp): 119589945 External Links: ENSG00000144843

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AHCY chr20 34280268 34311802 - CFL1 chr11 65823022 65862026 - COX7A2 chr6 75237675 75250323 - ECHDC2 chr1 52895910 52927212 - EDARADD chr1 236348257 236502915 + FCER2 chr19 7688758 7702146 - FTL chr19 48965309 48966879 + MFSD12 chr19 3538261 3574290 - MRM2 chr7 2234195 2242205 - MRPS26 chr20 3046052 3048250 + MYO18A chr17 29071124 29180412 - NACA2 chr17 61590421 61591219 - NCL chr2 231453531 231483641 - PGRMC1 chrX 119236245 119244466 + PSME1 chr14 24136163 24138967 + RACK1 chr5 181236897 181248096 - RAF1 chr3 12583601 12664226 - RIOX2 chr3 97941818 97972457 - RPL37A chr2 216498825 216579180 + RPLP0 chr12 120196699 120201235 - RPS2 chr16 1962058 1964841 - RPS25 chr11 119015712 119018691 - RSRC2 chr12 122503454 122527000 - SIAH2 chr3 150741125 150763477 - SLC25A6 chrX 1386152 1392113 - STARD7 chr2 96184859 96208825 - SUB1 chr5 32531633 32604079 + TMSB4X chrX 12975110 12977227 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.