exRNAdisease

Entry Detail

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General Information

Database ID: exR0428957 RNA Name: ADPRHL2 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 36088892 End Site(bp): 36093932 External Links: ENSG00000116863

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS6KL1 chr14 74903951 74923302 - VDAC2 chr10 75210154 75231448 + MT-ND3 chrMT 10059 10404 + ANAPC1 chr2 111611639 111884690 - TESC chr12 117038923 117099479 - HCFC2 chr12 104064531 104106524 + ATP5F1B chr12 56638175 56645984 - SRRT chr7 100875103 100888664 + CDK4 chr12 57747727 57756013 - RAB14 chr9 121178133 121223014 - OXSM chr3 25782917 25794534 + OAZ2 chr15 64687573 64703281 - CA12 chr15 63321378 63381846 - TTC28 chr22 27978014 28679865 - MIGA1 chr1 77779624 77879539 + CPZ chr4 8592660 8619759 + MCM5 chr22 35400134 35425431 + BRWD1 chr21 39184176 39321559 - IDI1 chr10 1039152 1049170 - STX16 chr20 58651253 58679526 + HLA-DQB1 chr6 32659467 32668383 - TNFRSF1A chr12 6328757 6342114 - STRAP chr12 15882387 15903478 + HLA-B chr6 31269491 31357188 - SPCS1 chr3 52704955 52711148 + TAGLN2 chr1 159918107 159925732 - RNASEK chr17 7012417 7014532 + EID2 chr19 39538707 39540161 - C1orf21 chr1 184387029 184629019 + SLC7A5 chr16 87830023 87869507 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC144548.1 chr12 110387463 110445548 - AL035458.2 chr20 34234840 34281173 - LINC01641 chr1 227393554 227431035 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.