exRNAdisease

Entry Detail

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General Information

Database ID: exR0428965 RNA Name: ADRM1 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 62302093 End Site(bp): 62308862 External Links: ENSG00000130706

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DDIT4 chr10 72273924 72276036 + MIER2 chr19 301444 344815 - TOPBP1 chr3 133598175 133662380 - HLA-B chr6 31269491 31357188 - NPLOC4 chr17 81556887 81648465 - P2RY11 chr19 10111693 10115372 + TAGLN2 chr1 159918107 159925732 - SREBF2 chr22 41833079 41907307 + TUBA1B chr12 49127782 49131397 - DDX49 chr19 18919705 18929189 + SELENOH chr11 57741250 57743554 + U2AF2 chr19 55654146 55674715 + RPS9 chr19 54200809 54249003 + MT-ND3 chrMT 10059 10404 + PLEC chr8 143915147 143976734 - TEX261 chr2 70985942 70994873 - OTUB1 chr11 63985853 64001811 + GNAO1 chr16 56191489 56357444 + GABARAP chr17 7240008 7242449 - VPS28 chr8 144423601 144428563 - ENO1 chr1 8861000 8879190 - TMEM8B chr9 35814451 35865518 + HSP90AB1 chr6 44246166 44253888 + TMEM120B chr12 121712752 121783001 + NDUFV1 chr11 67605653 67612554 + EMG1 chr12 6970913 6997428 + MTREX chr5 55307989 55425579 + MT-CO3 chrMT 9207 9990 + RGMB chr5 98768650 98798643 + ACAP3 chr1 1292390 1309609 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC139530.1 chr17 81701324 81703300 - BX284668.2 chr1 16870945 16883659 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.