exRNAdisease

Entry Detail

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General Information

Database ID: exR0428966 RNA Name: ADSL RNA Type: mRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 40346500 End Site(bp): 40390463 External Links: ENSG00000239900

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MADD chr11 47269161 47330031 + HDGFL3 chr15 83112738 83207823 - CLTC chr17 59619689 59696956 + MTRNR2L10 chrX 55181392 55182442 - HNRNPR chr1 23303771 23344336 - TOMM7 chr7 22812628 22822852 - MAPK6 chr15 51952106 52067375 + STK11 chr19 1177558 1228431 + SAP30 chr4 173369969 173377532 + PPIAL4F chr1 144592868 144593652 + SND1 chr7 127652194 128092609 + PPP1R18 chr6 30676389 30687895 - BAG6 chr6 31639028 31652705 - PSMD4 chr1 151254703 151267479 + AHCY chr20 34280268 34311802 - AC104452.1 chr3 49416777 49429314 - NICN1 chr3 49422946 49429326 - ERG28 chr14 75649791 75660876 - SGSM3 chr22 40370591 40410289 + PFN2 chr3 149964904 150050788 - RPS27A chr2 55231903 55235853 + TPM3 chr1 154155304 154194648 - PHF19 chr9 120855651 120894896 - ZNF20 chr19 12092843 12140355 - PCCA chr13 100089015 100530437 + GIPC1 chr19 14477760 14496149 - EEF1A1 chr6 73515750 73523797 - DNAJA3 chr16 4425805 4456775 + EZR chr6 158765741 158819368 - SLC25A17 chr22 40769630 40819399 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-193a-5p chr17 31560016 31560037 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL031595.3 chr22 44139365 44153626 + AL050341.2 chr1 40256427 40257967 - AL139819.1 chr10 100335563 100346390 - AL353759.1 chr6 26160765 26172802 - MIR205HG chr1 209428817 209432838 + NFYC-AS1 chr1 40690380 40692066 - SNHG25 chr17 64145970 64146476 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.