exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428971 RNA Name: AEBP2 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 19404045 End Site(bp): 19720801 External Links: ENSG00000139154

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DDX55 chr12 123602077 123620943 + NCKAP1 chr2 182909115 183038858 - AC092329.3 chr19 23222755 23274221 - FUS chr16 31180110 31194871 + HLA-F chr6 29722775 29738528 + EMD chrX 154379273 154381523 + MT-CO2 chrMT 7586 8269 + MSH5-SAPCD1 chr6 31740020 31764851 + BLOC1S2 chr10 100273280 100286680 - RAB11FIP4 chr17 31391675 31538211 + NYNRIN chr14 24399003 24419283 + ZNF724 chr19 23221599 23250390 - RPS28 chr19 8321158 8323340 + IRF2BPL chr14 77024543 77028708 - RACK1 chr5 181236897 181248096 - TTC9 chr14 70641916 70675366 + SAP18 chr13 21140514 21149084 + OCIAD1 chr4 48805212 48861817 + YBX1 chr1 42682418 42703805 + RHOBTB3 chr5 95713522 95824383 + NDUFB10 chr16 1959538 1961975 + HMGCR chr5 75336329 75362101 + NCS1 chr9 130172404 130237303 + TMEM43 chr3 14124940 14143679 + HNRNPA2B1 chr7 26173057 26201529 - COPB2 chr3 139355600 139389680 - NETO1 chr18 72742314 72868146 - RPL28 chr19 55385345 55403250 + RASGEF1C chr5 180100795 180209211 - DNAJB11 chr3 186567403 186585800 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL139260.2 chr1 38839333 38874494 - AL139819.1 chr10 100335563 100346390 - AL357078.2 chr1 65003470 65004087 - LINC01694 chr21 45593654 45603088 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.