exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428982 RNA Name: AFG3L2 RNA Type: mRNA Chromosome: chr18 Starnd: - Coordinate: Start Site(bp): 12328944 End Site(bp): 12377227 External Links: ENSG00000141385

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS18 chr6 33272075 33276511 + RPS23 chr5 82273320 82278396 - SOX11 chr2 5692384 5701385 + MT-CO2 chrMT 7586 8269 + RPL3 chr22 39312882 39320389 - N4BP2L2 chr13 32432417 32538885 - CHMP5 chr9 33264879 33282070 + PEAK1 chr15 77100656 77420144 - PPP1CB chr2 28751640 28802940 + GDI2 chr10 5765223 5842132 - PITX1 chr5 135027734 135034813 - NUP107 chr12 68686951 68745809 + DYNLL1 chr12 120469850 120498493 + CAPN2 chr1 223701593 223776018 + CSDE1 chr1 114716913 114758676 - ALDOA chr16 30064164 30070457 + SLC41A1 chr1 205789094 205813748 - TRAPPC1 chr17 7930345 7932123 - ADH5 chr4 99070978 99088801 - RPL35 chr9 124857880 124861981 - LCP1 chr13 46125920 46211871 - GAPDH chr12 6534512 6538374 + FLNA chrX 154348524 154374638 - BTG2 chr1 203305491 203309602 + FASN chr17 82078338 82098294 - C17orf49 chr17 7014495 7017525 + HK2 chr2 74834127 74893359 + YBX1 chr1 42682418 42703805 + THOC5 chr22 29505879 29555216 - PTTG1IP chr21 44849585 44873903 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC091564.7 chr11 6610883 6616594 - AP001496.2 chr18 5232876 5238526 - SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.