exRNAdisease

Entry Detail

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General Information

Database ID: exR0428983 RNA Name: AFMID RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 78187317 End Site(bp): 78207701 External Links: ENSG00000183077

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDOA chr16 30064164 30070457 + C8orf88 chr8 90958471 90985238 - CCT7 chr2 73233420 73253021 + CFL1 chr11 65823022 65862026 - CNOT1 chr16 58519951 58629885 - CRYBG2 chr1 26321698 26360080 - CSRP2 chr12 76858709 76879023 - EEF1D chr8 143579697 143599541 - FLNA chrX 154348524 154374638 - GTPBP3 chr19 17334920 17342731 + HLA-DPB1 chr6 33075990 33089696 + HOXD9 chr2 176122719 176124937 + LMNB1 chr5 126776623 126837020 + LPCAT1 chr5 1456480 1523962 - MAP3K11 chr11 65597756 65615382 - MYO1C chr17 1464186 1492686 - NCBP3 chr17 3802158 3846246 - PCNP chr3 101574180 101594465 + PPIA chr7 44796680 44824564 + RANBP2 chr2 108719482 108785809 + RBM5 chr3 50088919 50119021 + SIPA1L1 chr14 71320449 71741229 + SRA1 chr5 140537340 140558252 - TLR7 chrX 12867072 12890361 + UHRF1BP1 chr6 34792015 34883138 + UQCRHL chr1 15807169 15809348 - USF2 chr19 35268962 35279821 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL021707.3 chr22 38734730 38738990 + RMRP chr9 35657751 35658018 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.