exRNAdisease

Entry Detail

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General Information

Database ID: exR0428988 RNA Name: AGAP3 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 151085831 End Site(bp): 151144436 External Links: ENSG00000133612

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZNF703 chr8 37695782 37700019 + INTS1 chr7 1470277 1504389 - AC010646.1 chr19 17235940 17255448 - RNF11 chr1 51236273 51273447 + SLC31A1 chr9 113221544 113264492 + GFM1 chr3 158644278 158692575 + NR2F6 chr19 17231883 17245940 - DOCK1 chr10 126905409 127452517 + TMEM181 chr6 158536436 158635428 + TMEM241 chr18 23197144 23437961 - CDC25A chr3 48157146 48188417 - POU5F1B chr8 127322183 127420066 + LONP1 chr19 5691834 5720572 - KRT10 chr17 40818117 40822614 - XYLT2 chr17 50346126 50363138 + KDM4B chr19 4969113 5153598 + BSG chr19 571277 583493 + RPS6 chr9 19375715 19380236 - PDGFA chr7 497258 520296 - FAM219B chr15 74899992 74906883 - HOXD11 chr2 176104216 176109754 + ADA chr20 44619522 44652233 - HMGA1 chr6 34236873 34246231 + CDK18 chr1 205504595 205532793 + SLC25A39 chr17 44319625 44324870 - ADIPOR1 chr1 202940826 202958572 - MT-ND4L chrMT 10470 10766 + INA chr10 103277138 103290346 + WDR6 chr3 49007062 49015953 + BUB3 chr10 123154402 123170467 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-299-5p chr14 101023800 101023821 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022400.3 chr10 73674295 73730466 - AC087741.1 chr17 80200673 80205949 - AC079949.1 chr12 127142029 127146532 - AL355472.2 chr1 234357006 234365828 + AL356488.2 chr1 109100193 109100619 + FGD5-AS1 chr3 14920347 14948424 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.