exRNAdisease

Entry Detail

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General Information

Database ID: exR0428989 RNA Name: AGAP4 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 45825594 End Site(bp): 45853875 External Links: ENSG00000188234

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AGAP1 chr2 235494043 236131800 + AGAP5 chr10 73674285 73698159 - AGAP6 chr10 49982190 50010499 + AGAP9 chr10 47501854 47523638 - BMS1 chr10 42782795 42834937 + BSG chr19 571277 583493 + CCT3 chr1 156308968 156367873 - CDC42 chr1 22025511 22101360 + CNBP chr3 129169484 129183922 - FASN chr17 82078338 82098294 - FZD9 chr7 73433778 73436120 + HYPK chr15 43796142 43803043 + KIAA1522 chr1 32741830 32774970 + MATR3 chr5 139273752 139331671 + NONO chrX 71283192 71301168 + PHF3 chr6 63635820 63779336 + RPL37 chr5 40825262 40835222 - RPS2 chr16 1962058 1964841 - RPS9 chr19 54200809 54249003 + SERF2 chr15 43777087 43802589 + TSR1 chr17 2322396 2336657 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022400.3 chr10 73674295 73730466 - AGAP11 chr10 86970741 87010126 + AL136982.1 chr10 86992406 87010203 + AC135983.2 chr15 32398956 32435233 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.