exRNAdisease

Entry Detail

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General Information

Database ID: exR0428997 RNA Name: AGBL5 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 27042364 End Site(bp): 27070622 External Links: ENSG00000084693

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CD151 chr11 832887 839831 + WDR70 chr5 37379285 37753435 + PCNA chr20 5114953 5126626 - MRPL20 chr1 1401909 1407293 - EIF4B chr12 53006158 53042209 + CBS chr21 43053191 43076943 - SMC4 chr3 160399274 160434954 + SCD chr10 100347233 100364826 + AMMECR1L chr2 127861630 127885922 - LIFR chr5 38474668 38608354 - XPO6 chr16 28097979 28211920 - HNRNPA1 chr12 54280193 54287088 + IGFBP2 chr2 216632828 216664436 + TALDO1 chr11 747415 765012 + SYVN1 chr11 65121780 65134533 - RAB8A chr19 16111889 16134234 + FNBP1 chr9 129887187 130043194 - POLR2E chr19 1086574 1095380 - SNX25 chr4 185204237 185370185 + FAM76B chr11 95768953 95790409 - RPL4 chr15 66498015 66524532 - CREBZF chr11 85659708 85682908 - SNU13 chr22 41673933 41690504 - PSMB5 chr14 23016543 23035230 - TOX4 chr14 21476597 21499175 + RPL10 chrX 154389955 154409168 + ENTPD4 chr8 23385783 23457695 - URGCP-MRPS24 chr7 43866558 43906589 - MRPS24 chr7 43866558 43869893 - TIMM50 chr19 39480412 39493785 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC026362.1 chr12 122975320 122982907 + AL139819.1 chr10 100335563 100346390 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.