exRNAdisease

Entry Detail

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General Information

Database ID: exR0428999 RNA Name: AGFG1 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 227472152 End Site(bp): 227561214 External Links: ENSG00000173744

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTRNR2L4 chr16 3370979 3372668 - MRPS7 chr17 75261674 75266376 + PCDH7 chr4 30720415 31146805 + GNAS chr20 58839718 58911192 + COMMD1 chr2 61888724 62147247 + FLOT2 chr17 28879335 28897733 - UBE2W chr8 73780097 73878910 - C6orf47 chr6 31658298 31660778 - TUBA1B chr12 49127782 49131397 - P2RX1 chr17 3896592 3916476 - NDUFS7 chr19 1383527 1395589 + BRD3 chr9 134030305 134068535 - CCDC127 chr5 196868 218153 - LAMP1 chr13 113297239 113323672 + LSP1 chr11 1852970 1892267 + RPSA chr3 39406716 39412542 + PIP4K2C chr12 57591174 57603418 + RACK1 chr5 181236897 181248096 - EZH2 chr7 148807383 148884321 - MEF2A chr15 99565417 99716466 + BSG chr19 571277 583493 + REXO1 chr19 1815248 1848483 - ID1 chr20 31605283 31606515 + MXD4 chr4 2247432 2262109 - RPL27A chr11 8682788 8714759 + FEM1B chr15 68277745 68295862 + RPS23 chr5 82273320 82278396 - AC116366.3 chr5 132410832 132646079 + MRPL10 chr17 47823272 47831541 - ATP5MPL chr14 103912288 103928269 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-106b-5p chr7 100094043 100094063 - hsa-miR-380-3p chr14 101025056 101025077 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-4492 chr11 118910765 118910781 + hsa-miR-5703 chr2 227472162 227472179 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AP001330.4 chr8 101208148 101208558 + GAS5 chr1 173858559 173868882 - HOXA-AS2 chr7 27107777 27134302 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.