exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429000 RNA Name: AGFG2 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 100539203 End Site(bp): 100568220 External Links: ENSG00000106351

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HK1 chr10 69269984 69401884 + DUSP2 chr2 96143169 96145440 - HMGA1 chr6 34236873 34246231 + ADCY3 chr2 24819169 24919839 - BLCAP chr20 37492472 37527931 - KCNQ5 chr6 72621792 73198851 + LASP1 chr17 38869859 38921770 + RPS5 chr19 58386400 58394806 + CORO1B chr11 67435510 67443821 - RBM42 chr19 35629030 35637686 + DDX5 chr17 64498254 64508199 - RPS19 chr19 41860255 41872925 + REEP5 chr5 112876385 112922289 - HLA-A chr6 29941260 29945884 + VPS4A chr16 69311350 69326939 + SLC12A8 chr3 125082636 125212864 - ZFP36L1 chr14 68787660 68796253 - HLA-E chr6 30489509 30494194 + ARID3A chr19 925781 975939 + RPL13 chr16 89560657 89566828 + PTPRCAP chr11 67435510 67437682 - SOX13 chr1 204073115 204127743 + NMT1 chr17 45051610 45109016 + CRKL chr22 20917407 20953747 + INAFM2 chr15 40323692 40326715 + CDK1 chr10 60778331 60794852 + TUBA1B chr12 49127782 49131397 - BASP1 chr5 17065598 17276843 + TMEM54 chr1 32894594 32901438 - TPT1 chr13 45333471 45341370 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009065.3 chr16 2091436 2095433 + TMEM147-AS1 chr19 35540738 35546029 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.