exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429001 RNA Name: AGGF1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 77029251 End Site(bp): 77065234 External Links: ENSG00000164252

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ASPM chr1 197084127 197146694 - RPL27A chr11 8682788 8714759 + PGK1 chrX 77910739 78129295 + TUBA1B chr12 49127782 49131397 - EIF5A chr17 7306999 7312463 + FP565260.6 chr21 5155499 5165472 - MYL6 chr12 56158161 56163496 + FP565260.2 chr21 5116343 5133805 - ESRP1 chr8 94641074 94707466 + SUB1 chr5 32531633 32604079 + BZW2 chr7 16646131 16706523 + ACTA1 chr1 229431245 229434098 - B2M chr15 44711487 44718877 + NEDD4L chr18 58044226 58401540 + HLA-A chr6 29941260 29945884 + MARCKSL1 chr1 32333839 32336233 - RPS9 chr19 54200809 54249003 + AC008581.2 chr5 77030902 77152155 + KIFC3 chr16 57758217 57863053 - SMC4 chr3 160399274 160434954 + PRRC1 chr5 127517609 127555089 + TCEAL4 chrX 103576231 103587736 + PPP2R5B chr11 64917553 64934475 + ERAL1 chr17 28855010 28861061 + PBX1 chr1 164555584 164899296 + ID1 chr20 31605283 31606515 + CCPG1 chr15 55340032 55408510 - RPL23A chr17 28719985 28724359 + ACTN1 chr14 68874143 68979440 - MIF chr22 23894383 23895227 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand FGD5-AS1 chr3 14920347 14948424 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.