exRNAdisease

Entry Detail

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General Information

Database ID: exR0429002 RNA Name: AGK RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 141551278 End Site(bp): 141655244 External Links: ENSG00000006530

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EXOSC6 chr16 70246778 70251940 - AL138752.2 chr9 37588413 38068687 - TUBA1C chr12 49188736 49274603 + TOMM5 chr9 37582646 37592604 - RTN3 chr11 63681446 63759891 + LSS chr21 46188141 46228824 - SESN3 chr11 95165513 95232541 - RPAP2 chr1 92299059 92402056 + CBX5 chr12 54230942 54280133 - TAF10 chr11 6606294 6612539 - ID2 chr2 8678845 8684461 + ZCCHC17 chr1 31296982 31364953 + RBM5 chr3 50088919 50119021 + ZNF426 chr19 9523223 9538645 - ITGAL chr16 30472719 30523185 + KDM1A chr1 23019443 23083689 + ITGB5 chr3 124761948 124901418 - ARIH2 chr3 48918821 48986382 + PUF60 chr8 143816344 143829352 - GALC chr14 87837820 87993665 - AL513165.2 chr9 37512547 37592469 - PSMA2 chr7 42916861 42932185 - LGR4 chr11 27365961 27472790 - C5orf38 chr5 2752131 2755397 + ABI1 chr10 26746593 26861087 - AC010132.3 chr7 42909273 42932174 - LSM4 chr19 18306230 18323274 - FBXO21 chr12 117141988 117190531 - MRPL15 chr8 54135241 54148514 + HNRNPL chr19 38836388 38852347 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC097634.1 chr3 71584943 71587409 + GUSBP11 chr22 23638487 23717356 - PURPL chr5 27217714 27496994 + SNHG1 chr11 62851984 62855953 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.