exRNAdisease

Entry Detail

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General Information

Database ID: exR0429003 RNA Name: AGL RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 99850361 End Site(bp): 99924023 External Links: ENSG00000162688

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FSD1 chr19 4304598 4323843 + ATP5F1B chr12 56638175 56645984 - MRPL16 chr11 59806140 59810778 - CTPS1 chr1 40979688 41012565 + MARCKSL1 chr1 32333839 32336233 - ERCC6 chr10 49454470 49539538 - APP chr21 25880550 26171128 - CRLS1 chr20 6006093 6040053 + NAT10 chr11 34105617 34147670 + EEF1A1 chr6 73515750 73523797 - PTOV1 chr19 49850735 49860744 + NUCKS1 chr1 205712822 205750182 - KLHL15 chrX 23983720 24027186 - PPIA chr7 44796680 44824564 + RPS8 chr1 44775251 44778779 + POLD3 chr11 74493851 74669117 + ANXA7 chr10 73375101 73414076 - TBKBP1 chr17 47694081 47712050 + CARD10 chr22 37490362 37519542 - IQSEC1 chr3 12897043 13283281 - BEX4 chrX 103215108 103217246 + MRPL13 chr8 120380761 120445402 - CIAPIN1 chr16 57428187 57447420 - MIGA2 chr9 129036621 129072082 + KIF3C chr2 25926598 25982749 - DTL chr1 212035553 212107400 + KHDRBS1 chr1 32013868 32060850 + UHMK1 chr1 162497251 162529631 + AURKAIP1 chr1 1373730 1375495 - PARP1 chr1 226360691 226408093 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302b-3p chr4 112648489 112648511 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC00910 chr17 43338741 43389199 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.