exRNAdisease

Entry Detail

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General Information

Database ID: exR0429008 RNA Name: AGO3 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 35930718 End Site(bp): 36072500 External Links: ENSG00000126070

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DVL3 chr3 184155377 184173614 + FBXL19 chr16 30923055 30948783 + ATAD3B chr1 1471765 1497848 + PPP1R12C chr19 55090914 55117637 - TXNIP chr1 145992435 145996579 - WASF2 chr1 27404230 27490167 - ADORA2B chr17 15944917 15975746 + MGLL chr3 127689062 128052190 - PDIA5 chr3 123067025 123225227 + SSR3 chr3 156540140 156555184 - MYCBP2 chr13 77044657 77327094 - SNRPN chr15 24823637 24978723 + DVL1 chr1 1335276 1349418 - RPL13 chr16 89560657 89566828 + ZNF775 chr7 150368790 150398630 + SLC5A6 chr2 27199587 27212958 - CAPN15 chr16 527712 554636 + PAICS chr4 56435741 56464579 + ALKBH6 chr19 36009120 36014239 - CHD3 chr17 7884796 7912760 + FAM126B chr2 200973718 201071671 - RIMBP3B chr22 21383374 21389478 + AC073111.4 chr7 150400702 150412470 + SPAG5 chr17 28577565 28599025 - YBX1 chr1 42682418 42703805 + PPA2 chr4 105369077 105474067 - MT-ND4L chrMT 10470 10766 + VPS13B chr8 99013266 99877580 + RPS3 chr11 75399515 75422280 + DIP2A chr21 46458891 46570015 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002116.1 chr19 36008638 36014235 - AC007952.4 chr17 19112000 19112636 - AC108136.1 chr8 122485515 122489815 - AC079949.1 chr12 127142029 127146532 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.