exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429010 RNA Name: AGPAT1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 32168212 End Site(bp): 32178096 External Links: ENSG00000204310

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NAP1L3 chrX 93670930 93673578 - UBC chr12 124911604 124917368 - ENO1 chr1 8861000 8879190 - TRIM71 chr3 32817997 32897824 + NEMP1 chr12 57055643 57088063 - DBN1 chr5 177456608 177474401 - DAG1 chr3 49468703 49535618 + ABHD17C chr15 80679684 80755621 + ATR chr3 142449007 142578733 - MT-ND1 chrMT 3307 4262 + SNRNP200 chr2 96274338 96321271 - TMPO chr12 98515512 98550379 + DHFR chr5 80626226 80654983 - PAK6 chr15 40217428 40277487 + NEK6 chr9 124257606 124353307 + APP chr21 25880550 26171128 - GMPS chr3 155870650 155944020 + ACTG1 chr17 81509971 81523847 - MFSD12 chr19 3538261 3574290 - RPS3 chr11 75399515 75422280 + RAI1 chr17 17681458 17811453 + CBX1 chr17 48070052 48101478 - SDHC chr1 161314257 161375340 + AL121753.1 chr20 35267885 35280043 - EDC4 chr16 67873052 67884499 + PTPN12 chr7 77537295 77640069 + COX7A2L chr2 42333546 42425088 - RPL31 chr2 101002229 101024032 + ELF1 chr13 40931924 41061440 - SIX4 chr14 60709539 60724351 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040162.3 chr16 67882461 67886367 + GATA3-AS1 chr10 8050450 8053484 - OIP5-AS1 chr15 41283990 41309737 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - ZNF436-AS1 chr1 23368997 23371839 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.