exRNAdisease

Entry Detail

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General Information

Database ID: exR0429011 RNA Name: AGPAT2 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 136673143 End Site(bp): 136687457 External Links: ENSG00000169692

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA7 chr19 1039997 1065572 + ARF1 chr1 228082660 228099212 + CSNK1E chr22 38290691 38318084 - DNAJB6 chr7 157335381 157417439 + ENO1 chr1 8861000 8879190 - EP300 chr22 41092592 41180077 + EZR chr6 158765741 158819368 - FTL chr19 48965309 48966879 + GEMIN5 chr5 154887411 154938211 - ILF3 chr19 10654261 10692417 + ITM2C chr2 230864639 230879248 + MTA1 chr14 105419820 105470729 + MYD88 chr3 38138478 38143022 + NELFE chr6 31952087 31959038 - NKX3-2 chr4 13540830 13544508 - PLXNA3 chrX 154458281 154477779 + POLD1 chr19 50384204 50418018 + QPRT chr16 29663279 29698699 + RPL13A chr19 49487554 49492308 + RPS15 chr19 1438358 1440494 + SRSF4 chr1 29147743 29181900 - TNK2 chr3 195863364 195911945 - TRAPPC12 chr2 3379675 3485094 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019205.1 chr6 73263212 73301789 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.