exRNAdisease

Entry Detail

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General Information

Database ID: exR0429012 RNA Name: AGPAT3 RNA Type: mRNA Chromosome: chr21 Starnd: + Coordinate: Start Site(bp): 43865223 End Site(bp): 43987592 External Links: ENSG00000160216

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TUBB chr6 30720352 30725426 + WDR54 chr2 74421678 74425755 + RPLP1 chr15 69452814 69456205 + CARD9 chr9 136361903 136373681 - VAPB chr20 58389229 58451101 + IPO9 chr1 201829149 201884291 + KCTD3 chr1 215567304 215621807 + IMP3 chr15 75639085 75648706 - CLN3 chr16 28474111 28495575 - OSGEP chr14 20446401 20455089 - PPRC1 chr10 102132994 102150333 + CKLF chr16 66552563 66566251 + PDIA4 chr7 149003062 149028662 - RBM15 chr1 110338506 110346681 + RPL27A chr11 8682788 8714759 + ANKRD28 chr3 15667236 15859771 - HLA-B chr6 31269491 31357188 - BHLHE40 chr3 4979437 4985323 + SQSTM1 chr5 179806398 179838078 + RER1 chr1 2391775 2405442 + LAMC1 chr1 183023420 183145592 + RUNDC1 chr17 42980565 42993690 + POMK chr8 43093506 43123434 + GON4L chr1 155749662 155859400 - ACAP3 chr1 1292390 1309609 - DTNBP1 chr6 15522801 15663058 - PIK3R2 chr19 18153163 18170532 + ACIN1 chr14 23058564 23095614 - AC007192.1 chr19 18153158 18178117 + SPC24 chr19 11131520 11155808 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL049840.4 chr14 103694516 103695050 - AC010326.4 chr19 57867038 57868172 - AL355075.4 chr14 20343048 20343685 - LINC00665 chr19 36313067 36331770 - LINC01754 chr20 47391925 47412327 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.