exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429013 RNA Name: AGPAT4 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 161129967 End Site(bp): 161274061 External Links: ENSG00000026652

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CLIC1 chr6 31730581 31739763 - TMEM237 chr2 201620184 201643570 - EIF4G2 chr11 10797050 10808940 - METAP1 chr4 98995659 99062809 + TNFRSF13B chr17 16929816 16972118 - ILF2 chr1 153661788 153671028 - SPAG16 chr2 213284379 214410501 + FASN chr17 82078338 82098294 - DCK chr4 70992538 71030914 + RPL13 chr16 89560657 89566828 + HEXIM1 chr17 45148502 45152101 + DDB1 chr11 61299451 61342596 - PRR14 chr16 30650717 30656440 + RPS27A chr2 55231903 55235853 + SYMPK chr19 45815410 45863194 - SNRPD2 chr19 45687454 45692569 - RALY chr20 33993646 34108308 + BSG chr19 571277 583493 + RFT1 chr3 53088483 53130453 - LRRN1 chr3 3799431 3849834 + HP1BP3 chr1 20740266 20787323 - RTF1 chr15 41408408 41483563 + PHLDA1 chr12 76025447 76033932 - CLIP1 chr12 122271432 122422632 - GART chr21 33503931 33543491 - TOMM22 chr22 38681957 38685421 + CCDC102A chr16 57512181 57536571 - TXLNA chr1 32179675 32198285 + TMED9 chr5 177592203 177597242 + YIF1B chr19 38303558 38317273 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005394.2 chr19 28435388 28727680 - AL353719.1 chr10 99621055 99621918 + JAKMIP2-AS1 chr5 147559994 147662009 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.