exRNAdisease

Entry Detail

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General Information

Database ID: exR0429014 RNA Name: AGPAT5 RNA Type: mRNA Chromosome: chr8 Starnd: + Coordinate: Start Site(bp): 6708642 End Site(bp): 6761503 External Links: ENSG00000155189

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MFSD14B chr9 94374569 94461042 + RPL18A chr19 17859910 17864153 + NCL chr2 231453531 231483641 - PFN1 chr17 4945652 4949061 - GNA12 chr7 2728105 2844308 - RPL14 chr3 40457292 40468587 + MMP24OS chr20 35201745 35278131 - Z82206.1 chr22 39960397 39964718 + PRKAB1 chr12 119667864 119681624 + TMEM129 chr4 1715952 1721358 - PIGL chr17 16217191 16351797 + ARAP1 chr11 72685069 72793599 - MRPL30 chr2 99181152 99199561 + ELP3 chr8 28089673 28191156 + AC010422.3 chr19 12643831 12648397 - EEF1G chr11 62559596 62574086 - SLC9A3 chr5 470456 524449 - EIF2A chr3 150546678 150586016 + ARL6IP1 chr16 18791669 18801572 - TMEM241 chr18 23197144 23437961 - PKIG chr20 44531785 44624247 + ATF2 chr2 175072250 175168382 - LENG8 chr19 54448887 54462037 + TMEM248 chr7 66921225 66958551 + FKBP4 chr12 2794970 2805423 + TPT1 chr13 45333471 45341370 - ELL chr19 18442663 18522116 - DPY19L1 chr7 34928876 35038271 - CRYL1 chr13 20403666 20525873 - RACK1 chr5 181236897 181248096 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010442.1 chr5 466124 473098 - AC104461.1 chr1 200333193 200478669 + AL022311.1 chr22 37876148 37895563 + AC116565.1 chr4 577168 618076 + ESRG chr3 54632122 54639857 - MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.