exRNAdisease

Entry Detail

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General Information

Database ID: exR0429015 RNA Name: AGPS RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 177392757 End Site(bp): 177559299 External Links: ENSG00000018510

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand C2orf81 chr2 74414176 74421591 - ZDHHC8 chr22 20129456 20148007 + HES1 chr3 194136148 194138732 + AP2M1 chr3 184174689 184184091 + NDUFB11 chrX 47142216 47145504 - RPS3A chr4 151099624 151104642 + NUDT15 chr13 48037726 48047221 + HMGCR chr5 75336329 75362101 + OXA1L chr14 22766522 22773042 + RPL27A chr11 8682788 8714759 + RAB7A chr3 128726183 128814798 + RSRC2 chr12 122503454 122527000 - CDCA7 chr2 173354820 173368997 + DMWD chr19 45782947 45792845 - NCOR2 chr12 124324415 124567589 - PSMC6 chr14 52707178 52728590 + ATF4 chr22 39519695 39522685 + EIF4G3 chr1 20806292 21176888 - RPS24 chr10 78033760 78056813 + ANAPC4 chr4 25377213 25418498 + KHSRP chr19 6413348 6424794 - PSMB7 chr9 124353465 124415444 - TRAP1 chr16 3651639 3717553 - NCAPD2 chr12 6493356 6531955 + FEZF2 chr3 62369681 62374324 - ENO1 chr1 8861000 8879190 - GPR176 chr15 39799008 39920266 - HSPA4 chr5 133052013 133106449 + RPL12 chr9 127447674 127451406 - PARP2 chr14 20343582 20357905 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + AC138932.3 chr16 14909887 14911345 - AP005263.1 chr18 9102736 9254346 + LINC00910 chr17 43338741 43389199 - LINC01641 chr1 227393554 227431035 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.