exRNAdisease

Entry Detail

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General Information

Database ID: exR0429019 RNA Name: AGTPBP1 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 85546539 End Site(bp): 85742029 External Links: ENSG00000135049

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COL5A1 chr9 134641803 134844843 + EEF2 chr19 3976056 3985463 - EPOP chr17 38671703 38674957 - CCDC88C chr14 91271323 91417844 - TADA2B chr4 7041899 7057952 + HNRNPK chr9 83968083 83980616 - RPS27A chr2 55231903 55235853 + PSMD3 chr17 39980807 39997959 + VAMP3 chr1 7771296 7781432 + GPRC5B chr16 19856691 19886167 - CCDC189 chr16 30757423 30762221 - CCAR2 chr8 22604632 22621514 + CAND2 chr3 12796472 12871916 + DNAJB6 chr7 157335381 157417439 + TPT1 chr13 45333471 45341370 - METTL7A chr12 50923472 50932510 + PLXNA3 chrX 154458281 154477779 + SMARCD1 chr12 50085200 50100707 + ST13 chr22 40824535 40856639 - U2SURP chr3 142964497 143060725 + ZNF234 chr19 44141554 44160313 + ABHD14B chr3 51968510 51983409 - TYMS chr18 657653 673578 + GATAD2B chr1 153789030 153923360 - STAT1 chr2 190908460 191020960 - RANBP1 chr22 20115938 20127355 + VTI1B chr14 67647085 67674820 - IRF4 chr6 391752 411443 + C1orf210 chr1 43281877 43285617 - CALM3 chr19 46601074 46610782 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand PDCD4-AS1 chr10 110869868 110872233 - ZFAS1 chr20 49278178 49299600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.