exRNAdisease

Entry Detail

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General Information

Database ID: exR0429022 RNA Name: AGTRAP RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 11736084 End Site(bp): 11754802 External Links: ENSG00000177674

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand LDHA chr11 18394560 18408425 + STK4 chr20 44966479 45080021 + ACPP chr3 132317369 132368298 + HOXB1 chr17 48528526 48531011 - TMSB4X chrX 12975110 12977227 + PAFAH1B3 chr19 42297033 42303546 - KDM3A chr2 86440647 86492716 + ICE1 chr5 5420664 5490220 + CCDC88C chr14 91271323 91417844 - TUBA1C chr12 49188736 49274603 + POGK chr1 166839447 166856344 + NUCB1 chr19 48900312 48923372 + RPL30 chr8 98024851 98046469 - HSF1 chr8 144291591 144314720 + PABPC3 chr13 25095868 25099254 + PABPN1 chr14 23321289 23326185 + KRT19 chr17 41523617 41528308 - SLC2A13 chr12 39755025 40106089 - UBE2T chr1 202331657 202341980 - XPC chr3 14145147 14178783 - FUS chr16 31180110 31194871 + TJAP1 chr6 43477523 43506556 + MAD2L2 chr1 11674480 11691650 - CNPY3 chr6 42929192 42939294 + STAT5B chr17 42199177 42276707 - SCARB1 chr12 124776856 124882668 - IQGAP1 chr15 90388242 90502239 + SND1 chr7 127652194 128092609 + HLA-B chr6 31269491 31357188 - APEH chr3 49674014 49683971 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-188-5p chrX 50003517 50003537 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-324-5p chr17 7223343 7223364 - hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-129-2-3p chr11 43581450 43581471 + hsa-miR-330-5p chr19 45639049 45639070 - hsa-miR-628-5p chr15 55372991 55373012 - hsa-miR-541-3p chr14 101064548 101064569 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + MIR663AHG chr20 26167817 26251546 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.