exRNAdisease

Entry Detail

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General Information

Database ID: exR0429024 RNA Name: AHCTF1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 246839098 End Site(bp): 246931967 External Links: ENSG00000153207

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADGRL2 chr1 81306160 81992436 + BBX chr3 107522936 107811339 + CTNND1 chr11 57753243 57819546 + DESI2 chr1 244653103 244709033 + DIP2A chr21 46458891 46570015 + DYM chr18 49041474 49461347 - FAF1 chr1 50437028 50960267 - FAM72D chr1 145095974 145112696 + FKBP8 chr19 18531751 18544077 - GANAB chr11 62624826 62646726 - GATA4 chr8 11676959 11760002 + KLHL42 chr12 27780048 27803040 + OAZ1 chr19 2269509 2273490 + OS9 chr12 57693955 57721557 + PML chr15 73994673 74047827 + PPP2R2A chr8 26291508 26372680 + PTMA chr2 231706895 231713541 + RPL18 chr19 48615328 48619184 - RPS8 chr1 44775251 44778779 + RRM2B chr8 102204502 102238961 - RTN3 chr11 63681446 63759891 + SDHC chr1 161314257 161375340 + SRSF9 chr12 120461672 120469748 - STK35 chr20 2101827 2177038 + UBE4B chr1 10032832 10181239 + ZSWIM8 chr10 73785582 73801797 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand FTX chrX 73940435 74293574 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.