exRNAdisease

Entry Detail

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General Information

Database ID: exR0429025 RNA Name: AHCY RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 34280268 End Site(bp): 34311802 External Links: ENSG00000101444

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASDHPPT chr11 106075501 106098699 + AASS chr7 122073549 122144255 - AATK chr17 81110487 81166221 - ABRACL chr6 139028745 139043302 + AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC011448.1 chr19 19516227 19536076 + AC015813.2 chr17 57989038 58007246 - AC087289.3 chr17 75898645 75930129 - AC104109.3 chr5 134167170 134226071 - AC105052.3 chr7 102637049 102671641 - AC120057.2 chr17 7240427 7244635 - ACAA2 chr18 49782164 49813953 - ACAP1 chr17 7336529 7351477 + ACKR3 chr2 236567787 236582354 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADIPOR1 chr1 202940826 202958572 - ADIPOR2 chr12 1688574 1788674 + ADPRH chr3 119579268 119589945 + ADPRHL2 chr1 36088892 36093932 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AGO1 chr1 35869808 35930532 + AL022238.4 chr22 40346529 40410054 + AL359922.1 chr9 21802636 22029594 + ALDH18A1 chr10 95605941 95656711 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC008443.1 chr5 181246507 181272167 + AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC067852.2 chr17 42552436 42554748 - AC091564.2 chr11 6603642 6604420 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL035458.2 chr20 34234840 34281173 - AL118516.1 chr22 46761894 46762563 - AC135178.6 chr17 8277763 8278436 + AP005263.1 chr18 9102736 9254346 + CYTOR chr2 87454781 87636740 + DHRS4-AS1 chr14 23938219 24052555 - ESRG chr3 54632122 54639857 - LINC00545 chr13 30880912 30883395 + LINC00941 chr12 30755167 30802602 + LINC01278 chrX 63222993 63561095 - LINC01578 chr15 92819540 92899701 + NOP14-AS1 chr4 2934882 2961738 + SNHG14 chr15 24978583 25420336 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.