exRNAdisease

Entry Detail

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General Information

Database ID: exR0429026 RNA Name: AHCYL1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 109984765 End Site(bp): 110023742 External Links: ENSG00000168710

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HDGF chr1 156742109 156766925 - PAK2 chr3 196739857 196832647 + DCUN1D4 chr4 51843000 51916837 + NUFIP2 chr17 29255839 29294148 - ATP5MF chr7 99448475 99466331 - NACA chr12 56712427 56731628 - RPLP0 chr12 120196699 120201235 - NECAB3 chr20 33657087 33674463 - TPT1 chr13 45333471 45341370 - INTS10 chr8 19817391 19852083 + RPS12 chr6 132814569 132817564 + RRM2B chr8 102204502 102238961 - ERP44 chr9 99979185 100099000 - UBXN6 chr19 4444999 4457794 - TUBA1B chr12 49127782 49131397 - ATP5PO chr21 33903453 33915814 - HSP90AB1 chr6 44246166 44253888 + IMMT chr2 86143932 86195770 - TKT chr3 53224712 53256052 - MT-ND4 chrMT 10760 12137 + HLA-DRB1 chr6 32578769 32589848 - AL136454.1 chr1 192716132 192716653 + SYNCRIP chr6 85607785 85643792 - SLC1A5 chr19 46774883 46788594 - NRM chr6 30688047 30691420 - OPA3 chr19 45527427 45602212 - PABPN1 chr14 23321289 23326185 + DDIT4 chr10 72273924 72276036 + RPS10-NUDT3 chr6 34284887 34426071 - IDH1 chr2 208236227 208266074 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-574-5p chr4 38868056 38868078 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC073529.1 chrX 10847578 11111220 - AC092490.1 chr12 8788253 8795789 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AC079354.2 chr2 202178660 202179391 - LINC02190 chr16 31542748 31553604 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.