exRNAdisease

Entry Detail

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General Information

Database ID: exR0429028 RNA Name: AHDC1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 27534035 End Site(bp): 27604431 External Links: ENSG00000126705

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTRNR2L10 chrX 55181392 55182442 - EFNB2 chr13 106489745 106535662 - DCUN1D4 chr4 51843000 51916837 + PI4KA chr22 20707691 20859417 - PABPC1 chr8 100685816 100722809 - PTBP1 chr19 797075 812327 + TMEM107 chr17 8172457 8176399 - ALDOA chr16 30064164 30070457 + ATRAID chr2 27212027 27217178 + LOXL3 chr2 74532258 74555690 - FAM32A chr19 16185380 16192046 + EDARADD chr1 236348257 236502915 + EDC4 chr16 67873052 67884499 + NUP188 chr9 128947699 129007096 + ARHGAP33 chr19 35774532 35788822 + SLC25A33 chr1 9539465 9585173 + EP400 chr12 131949942 132080460 + AIF1L chr9 131096476 131123152 + PRR14L chr22 31676256 31750140 - LPGAT1 chr1 211743457 211830763 - RPS5 chr19 58386400 58394806 + HCLS1 chr3 121631399 121660927 - TOE1 chr1 45340052 45343973 + CDK10 chr16 89680737 89696354 + ATP1A1 chr1 116372668 116410261 + NCBP1 chr9 97633668 97673748 + CRTC1 chr19 18683678 18782333 + WDR45B chr17 82614562 82648553 - GMEB2 chr20 63587602 63627101 - RMI2 chr16 11249619 11381662 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-138-5p chr16 56858527 56858549 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC138932.3 chr16 14909887 14911345 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.