exRNAdisease

Entry Detail

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General Information

Database ID: exR0429030 RNA Name: AHNAK RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 62433542 End Site(bp): 62556235 External Links: ENSG00000124942

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SRRM2 chr16 2752626 2772538 + C15orf39 chr15 75195643 75212169 + DGKI chr7 137381037 137847092 - LRRC8A chr9 128882112 128918039 + PPP1R8 chr1 27830782 27851676 + COMT chr22 19941733 19969975 + SLC16A1 chr1 112911847 112957013 - RBM33 chr7 155644451 155781485 + PSMD8 chr19 38374536 38383824 + PSMB1 chr6 170535120 170553307 - DNMT3A chr2 25227855 25342590 - PABPC3 chr13 25095868 25099254 + TOR1AIP2 chr1 179839967 179877803 - APP chr21 25880550 26171128 - MPZL1 chr1 167721192 167791919 + DCAF8 chr1 160215715 160262549 - FBXO31 chr16 87326987 87392142 - SORL1 chr11 121452314 121633763 + RABEP1 chr17 5282265 5386340 + ARL2BP chr16 57245259 57253635 + HUWE1 chrX 53532096 53686728 - RACK1 chr5 181236897 181248096 - KDM6A chrX 44873177 45112602 + CCNG2 chr4 77157207 77433388 + TMEM132A chr11 60924463 60937159 + PPP6R1 chr19 55229779 55259017 - R3HCC1 chr8 23270120 23296279 + TTC38 chr22 46267961 46294008 + MFN2 chr1 11980181 12013514 + MORF4L2 chrX 103675496 103688158 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC010327.5 chr19 55216660 55221616 + AD000090.1 chr19 35557956 35581954 + AL139385.1 chr13 110613082 110616353 - LINC00174 chr7 66376044 66493566 - RMRP chr9 35657751 35658018 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.