exRNAdisease

Entry Detail

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General Information

Database ID: exR0429032 RNA Name: AHR RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 16916359 End Site(bp): 17346152 External Links: ENSG00000106546

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKR1A1 chr1 45550543 45570049 + AP3B1 chr5 78000525 78294755 - CAPRIN1 chr11 34051731 34102610 + CCDC91 chr12 28133249 28581511 + CNN3 chr1 94896949 94927223 - COMMD1 chr2 61888724 62147247 + DCAF6 chr1 167935783 168075843 + FLT4 chr5 180601506 180649624 - GAPDH chr12 6534512 6538374 + HMGB2 chr4 173331376 173334432 - LGALS9 chr17 27629798 27649560 + MED28 chr4 17614641 17634105 + NAGK chr2 71064344 71079808 + NOP53 chr19 47745546 47757058 + PTBP1 chr19 797075 812327 + RFTN1 chr3 16313574 16514026 - RPS23 chr5 82273320 82278396 - RPS5 chr19 58386400 58394806 + SLC2A3 chr12 7919230 7936187 - SRF chr6 43171269 43181506 + SRP9 chr1 225777813 225790468 + USP53 chr4 119212587 119295517 + YIPF6 chrX 68498562 68537282 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019117.3 chr7 17374867 17467256 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.