exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429033 RNA Name: AHRR RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 271670 End Site(bp): 438291 External Links: ENSG00000286169

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDOA chr16 30064164 30070457 + CARM1 chr19 10871513 10923070 + COQ2 chr4 83261536 83284914 - DDA1 chr19 17309518 17323298 + GATAD1 chr7 92447482 92460075 + GATM chr15 45361124 45402327 - HLA-C chr6 31268749 31272130 - HLA-DQA1 chr6 32628179 32647062 + KIF2C chr1 44739818 44767767 + LPGAT1 chr1 211743457 211830763 - MTMR3 chr22 29883155 30030866 + NAMPT chr7 106248298 106286326 - NDUFS7 chr19 1383527 1395589 + PDCD6 chr5 271621 314974 + PHB2 chr12 6965327 6970753 - PRKRIP1 chr7 102363872 102426676 + PUS7 chr7 105439661 105522271 - RPL11 chr1 23691742 23696835 + RPL13 chr16 89560657 89566828 + RPS19 chr19 41860255 41872925 + RPS8 chr1 44775251 44778779 + SDHA chr5 218241 257082 + STRAP chr12 15882387 15903478 + TAF1C chr16 84177847 84187070 - THAP7 chr22 20999104 21002196 - TRAPPC6A chr19 45162928 45178237 - TRIM65 chr17 75880335 75896951 - YIF1A chr11 66284580 66289145 - ZNF764 chr16 30553764 30558498 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MIR155HG chr21 25561909 25575168 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.