exRNAdisease

Entry Detail

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General Information

Database ID: exR0429034 RNA Name: AHSA1 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 77457870 End Site(bp): 77469472 External Links: ENSG00000100591

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ENO1 chr1 8861000 8879190 - RPS9 chr19 54200809 54249003 + OAZ1 chr19 2269509 2273490 + SDHC chr1 161314257 161375340 + RPLP0 chr12 120196699 120201235 - PIMREG chr17 6444441 6451469 + ST3GAL6 chr3 98732236 98821201 + MDK chr11 46380756 46383837 + ZNF608 chr5 124636913 124748807 - MT-ATP6 chrMT 8527 9207 + ALDOA chr16 30064164 30070457 + SIRPA chr20 1894167 1940592 + KRT19 chr17 41523617 41528308 - TTC7B chr14 90524564 90816479 - PCED1A chr20 2835314 2841190 - RPL27A chr11 8682788 8714759 + B2M chr15 44711487 44718877 + CCT4 chr2 61868085 61888671 - C9orf78 chr9 129827290 129835863 - IVNS1ABP chr1 185296388 185317273 - ZDHHC22 chr14 77131270 77142734 - CDCA7 chr2 173354820 173368997 + LCP1 chr13 46125920 46211871 - RPS26 chr12 56041351 56044697 + APH1A chr1 150265399 150269580 - LMNB2 chr19 2427638 2456959 - ATP5F1D chr19 1241746 1244825 + FTSJ3 chr17 63819433 63830012 - PTPRF chr1 43525187 43623666 + NOP10 chr15 34341713 34343177 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC239799.1 chr1 146235806 146237807 + AP001496.2 chr18 5232876 5238526 - MIR663AHG chr20 26167817 26251546 - RAB11B-AS1 chr19 8374373 8390685 - RMRP chr9 35657751 35658018 - SNHG5 chr6 85650491 85678932 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.