exRNAdisease

Entry Detail

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General Information

Database ID: exR0429036 RNA Name: AICDA RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 8602170 End Site(bp): 8612867 External Links: ENSG00000111732

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ERCC5 chr13 102807146 102876001 + UBE2Z chr17 48908407 48929056 + TAPBP chr6 33299694 33314387 - ALDH9A1 chr1 165662216 165698863 - ITM2C chr2 230864639 230879248 + ACTR1B chr2 97655939 97664044 - LGMN chr14 92703807 92748679 - ABL1 chr9 130713016 130887675 + AC027644.4 chr7 66628958 66811189 + RPL30 chr8 98024851 98046469 - ATP5MG chr11 118401606 118431496 + POMT2 chr14 77274956 77320884 - RPS16 chr19 39433137 39435949 - SMUG1 chr12 54121277 54189008 - UBA2 chr19 34428352 34471251 + DCAF1 chr3 51395867 51500002 - MT-ND4 chrMT 10760 12137 + NADSYN1 chr11 71453109 71524107 + AP001781.2 chr11 111786286 111879425 - GAPDH chr12 6534512 6538374 + NACA2 chr17 61590421 61591219 - TOP2A chr17 40388525 40417896 - GAS2L3 chr12 100573683 100628288 + POLG2 chr17 64477785 64497054 - ATP5F1C chr10 7788147 7807815 + RPL8 chr8 144789765 144792587 - MTRNR2L8 chr11 10507894 10509186 - OVOL1 chr11 65787063 65797214 + RABGEF1 chr7 66682164 66811464 + SLC25A3 chr12 98593591 98606379 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC02154 chrX 13266048 13303452 - MIR155HG chr21 25561909 25575168 + TSPOAP1-AS1 chr17 58324472 58415766 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.