exRNAdisease

Entry Detail

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General Information

Database ID: exR0429037 RNA Name: AIDA RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 222668013 End Site(bp): 222713210 External Links: ENSG00000186063

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EEF1A1 chr6 73515750 73523797 - RPS6 chr9 19375715 19380236 - SALL1 chr16 51135975 51151367 - PDIA6 chr2 10783391 10837977 - STRN4 chr19 46719511 46746994 - RARRES2 chr7 150338317 150341662 - SH2B2 chr7 102285091 102321711 + TMEM106C chr12 47963569 47968878 + HLA-B chr6 31269491 31357188 - URI1 chr19 29923644 30016612 + PHGDH chr1 119648411 119744226 + UBXN1 chr11 62676498 62679117 - EMD chrX 154379273 154381523 + MRPL13 chr8 120380761 120445402 - SMAD4 chr18 51028394 51085045 + EIF4G1 chr3 184314495 184335358 + FEM1B chr15 68277745 68295862 + RPL4 chr15 66498015 66524532 - RAB8B chr15 63189560 63267776 + RPL11 chr1 23691742 23696835 + PAK1IP1 chr6 10694972 10709782 + MIF chr22 23894383 23895227 + EPB41L5 chr2 120013077 120179119 + ATP2B1 chr12 89588049 89709300 - ZFP36L2 chr2 43222402 43226606 - ADAR chr1 154582057 154628013 - NSMCE1 chr16 27224994 27268772 - GPSM1 chr9 136327476 136359605 + CPNE3 chr8 86514435 86561498 + AHNAK chr11 62433542 62556235 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.