exRNAdisease

Entry Detail

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General Information

Database ID: exR0429038 RNA Name: AIF1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 31615217 End Site(bp): 31617021 External Links: ENSG00000204472

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + AC008403.1 chr19 48465837 48472431 + ANP32B chr9 97983341 98015943 + CCT7 chr2 73233420 73253021 + COX7A2L chr2 42333546 42425088 - CYTH2 chr19 48469208 48482314 + DAXX chr6 33318558 33323016 - GCK chr7 44143213 44198170 - IAH1 chr2 9473658 9496543 + LEF1 chr4 108047545 108168956 - NDUFA4 chr7 10931943 10940153 - NDUFB9 chr8 124539101 124580648 + RACK1 chr5 181236897 181248096 - RBPJ chr4 26163455 26435131 + RPL27A chr11 8682788 8714759 + RPL37A chr2 216498825 216579180 + RPLP2 chr11 809965 812880 + SIPA1L3 chr19 37907208 38208369 + SRP9 chr1 225777813 225790468 + TCF15 chr20 603797 610398 - TUBA1A chr12 49184795 49189080 - UQCC3 chr11 62670273 62673686 + ZNF322 chr6 26634383 26659752 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.