exRNAdisease

Entry Detail

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General Information

Database ID: exR0429040 RNA Name: AIFM1 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 130129362 End Site(bp): 130165887 External Links: ENSG00000156709

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FKBP8 chr19 18531751 18544077 - RPL13A chr19 49487554 49492308 + DAPK3 chr19 3958453 3971123 - RPS19 chr19 41860255 41872925 + RPS21 chr20 62387103 62388520 + TARS2 chr1 150487364 150507609 + CHKA chr11 68052859 68121444 - NUP50 chr22 45163925 45188017 + FADS2 chr11 61792980 61867354 + RPS28 chr19 8321158 8323340 + RPLP1 chr15 69452814 69456205 + MXI1 chr10 110207605 110287365 + RPL36 chr19 5674947 5691875 + BCAP31 chrX 153700492 153724565 - AKAP11 chr13 42272152 42323261 + EPS8L2 chr11 694438 727727 + ACTR3 chr2 113890063 113962596 + WDCP chr2 24029347 24049575 - HEATR1 chr1 236549005 236604516 - DEGS1 chr1 224175756 224193441 + CCNG1 chr5 163437569 163446151 + RBM14 chr11 66616582 66627347 + GPBP1 chr5 57173948 57264679 + PTPN7 chr1 202147013 202161588 - AC058822.1 chr4 53377839 54295272 + EVL chr14 99971449 100144236 + ZNF451 chr6 57086844 57170305 + HCLS1 chr3 121631399 121660927 - EGLN3 chr14 33924227 34462774 - OAZ1 chr19 2269509 2273490 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC064802.1 chr8 114282067 114295839 + AC013269.1 chr2 130530275 130537182 + ITGB2-AS1 chr21 44921051 44929678 + JPX chrX 73944182 74070408 + SNHG14 chr15 24978583 25420336 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.