exRNAdisease

Entry Detail

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General Information

Database ID: exR0429043 RNA Name: AIG1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 143060496 End Site(bp): 143341058 External Links: ENSG00000146416

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NARS2 chr11 78435968 78574874 - MYO1G chr7 44962662 44979088 - ARHGAP30 chr1 161046946 161069970 - AREL1 chr14 74653437 74713108 - UBE3A chr15 25333728 25439051 - ATP2B4 chr1 203626561 203744081 + DTWD1 chr15 49621037 49656232 + RND2 chr17 43025231 43032041 + CYP26A1 chr10 93073475 93077885 + RGS12 chr4 3293028 3439913 + MT-CO2 chrMT 7586 8269 + ATRX chrX 77504878 77786233 - AC131160.1 chr3 183815568 183884889 - HSP90AB1 chr6 44246166 44253888 + DPP8 chr15 65442463 65517704 - PPP1R8 chr1 27830782 27851676 + EIF4B chr12 53006158 53042209 + FKBP1A chr20 1368978 1393172 - TUBB chr6 30720352 30725426 + HS1BP3 chr2 20560448 20651130 - ARRB2 chr17 4710596 4721499 + RNH1 chr11 494512 507300 - BOD1 chr5 173607145 173616659 - RPLP1 chr15 69452814 69456205 + GNAS chr20 58839718 58911192 + WDR12 chr2 202874782 203014798 - SLC43A3 chr11 57406954 57427580 - ST3GAL2 chr16 70375977 70439237 - TEX10 chr9 100302077 100352942 - IGFBP4 chr17 40443450 40457725 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC137630.2 chr3 48979918 48983985 - HOTAIRM1 chr7 27095647 27100265 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.