exRNAdisease

Entry Detail

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General Information

Database ID: exR0429045 RNA Name: AIMP1 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 106315544 End Site(bp): 106349456 External Links: ENSG00000164022

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TBCK chr4 106041599 106316683 - MED19 chr11 57703714 57712323 - CD2AP chr6 47477789 47627263 + DENND1C chr19 6467207 6482557 - RCOR1 chr14 102592649 102730561 + PPTC7 chr12 110533245 110583318 - ANXA5 chr4 121667946 121696995 - TRAP1 chr16 3651639 3717553 - PTOV1 chr19 49850735 49860744 + TRAPPC6B chr14 39147811 39170532 - FBXO7 chr22 32474676 32498829 + CD79A chr19 41877279 41881372 + PRRC2C chr1 171485551 171593511 + UBE3C chr7 157138916 157269370 + LRPPRC chr2 43886224 43995989 - EPCAM chr2 47345158 47387601 + RPL26 chr17 8377516 8383213 - EEF1B2 chr2 206159585 206162928 + BBS5 chr2 169479480 169506655 + RCC1 chr1 28505943 28539300 + ARID4B chr1 235131634 235328219 - PPIE chr1 39692182 39763914 + ARHGAP9 chr12 57472264 57488814 - PDPR chr16 70113626 70162537 + HLA-C chr6 31268749 31272130 - EIF4B chr12 53006158 53042209 + RPL27A chr11 8682788 8714759 + B4GALT7 chr5 177600132 177610330 + CHEK2 chr22 28687743 28742422 - RPL4 chr15 66498015 66524532 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG16 chr17 76557764 76565348 + SNHG3 chr1 28505980 28510892 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.