exRNAdisease

Entry Detail

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General Information

Database ID: exR0429046 RNA Name: AIMP2 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 6009255 End Site(bp): 6023834 External Links: ENSG00000106305

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026954.2 chr17 7312661 7319174 - RPL36 chr19 5674947 5691875 + TFG chr3 100709331 100748964 + CCDC163 chr1 45493866 45500079 - RPL19 chr17 39200283 39204732 + PAICS chr4 56435741 56464579 + CDK16 chrX 47217860 47229997 + AC139530.2 chr17 81703371 81720539 + IMP3 chr15 75639085 75648706 - EPN1 chr19 55675226 55709858 + NDUFV1 chr11 67605653 67612554 + BFAR chr16 14632931 14669236 + PRR13 chr12 53441678 53446645 + NMT1 chr17 45051610 45109016 + EEF2 chr19 3976056 3985463 - FTSJ3 chr17 63819433 63830012 - CYP51A1 chr7 92112153 92134803 - BZW1 chr2 200810594 200827338 + MIF chr22 23894383 23895227 + MCL1 chr1 150574551 150579738 - DYNLL1 chr12 120469850 120498493 + SNX30 chr9 112750760 112881671 + SMO chr7 129188633 129213545 + GLUL chr1 182381704 182392206 - KDM4B chr19 4969113 5153598 + FBRS chr16 30658431 30670810 + RNASEK-C17orf49 chr17 7012635 7017520 + NFE2L1 chr17 48048329 48061545 + CTSB chr8 11842524 11869448 - CTNNBL1 chr20 37693955 37872129 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + ATP2B1-AS1 chr12 89708959 89712590 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + TPT1-AS1 chr13 45341345 45417975 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.