exRNAdisease

Entry Detail

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General Information

Database ID: exR0429047 RNA Name: AIP RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 67483026 End Site(bp): 67491103 External Links: ENSG00000110711

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EWSR1 chr22 29268009 29300525 + EMC10 chr19 50476400 50490870 + LDHA chr11 18394560 18408425 + ANKRD13D chr11 67289300 67302485 + EIF3F chr11 7970251 8001862 + MKNK2 chr19 2037465 2051244 - MAOA chrX 43654907 43746824 + DNA2 chr10 68414064 68472121 - PKM chr15 72199029 72231822 - AP2M1 chr3 184174689 184184091 + BCL2L13 chr22 17628855 17730855 + RPS3 chr11 75399515 75422280 + BHLHE22 chr8 64580365 64583627 + TMX2 chr11 57712593 57740973 + NOL6 chr9 33461353 33473930 - APH1A chr1 150265399 150269580 - DMAC1 chr9 7796500 7888380 - GLO1 chr6 38675925 38703145 - OXLD1 chr17 81665036 81666635 - HILPDA chr7 128455849 128458418 + UIMC1 chr5 176905005 177022633 - AP002990.1 chr11 62559603 62591531 - NOP53 chr19 47745546 47757058 + GTF2A2 chr15 59638062 59657541 - NIPSNAP1 chr22 29554808 29581327 - VSTM2A chr7 54542325 54571080 + SLC25A6 chrX 1386152 1392113 - LY6E chr8 143017982 143023832 + MADD chr11 47269161 47330031 + ALCAM chr3 105366909 105576900 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005785.1 chr19 15379076 15381194 + AD000090.1 chr19 35557956 35581954 + FBXL19-AS1 chr16 30919319 30923269 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.