exRNAdisease

Entry Detail

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General Information

Database ID: exR0429052 RNA Name: AJUBA RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 22971177 End Site(bp): 22982551 External Links: ENSG00000129474

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RXRA chr9 134317098 134440585 + RACK1 chr5 181236897 181248096 - ARL6IP4 chr12 122980060 122982913 + SORL1 chr11 121452314 121633763 + PISD chr22 31618491 31662432 - LDHA chr11 18394560 18408425 + TUBA1A chr12 49184795 49189080 - B2M chr15 44711487 44718877 + SUGP2 chr19 18990888 19034023 - HNRNPC chr14 21209136 21269494 - AC003006.1 chr19 57682045 57753575 + IFITM3 chr11 319676 327537 - VDAC1 chr5 133971871 134004975 - TPT1 chr13 45333471 45341370 - CACNG8 chr19 53963040 53990215 + HMGA1 chr6 34236873 34246231 + RAVER1 chr19 10316212 10333638 - PSMD10 chrX 108084207 108091549 - CNBP chr3 129169484 129183922 - CAPZA2 chr7 116811070 116922049 + SHMT1 chr17 18327860 18363563 - VPS4A chr16 69311350 69326939 + CMTM6 chr3 32481312 32502852 - GAPDH chr12 6534512 6538374 + ZNF551 chr19 57681969 57717301 + TRNP1 chr1 26993692 27000886 + CPNE1 chr20 35626031 35664956 - RPL13A chr19 49487554 49492308 + HIGD2A chr5 176388751 176389761 + DDB1 chr11 61299451 61342596 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC079949.1 chr12 127142029 127146532 - AP003392.4 chr11 119065263 119065677 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.