exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429053 RNA Name: AK1 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 127866486 End Site(bp): 127877675 External Links: ENSG00000106992

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17C chr15 80679684 80755621 + BCL11B chr14 99169287 99272197 - C9orf16 chr9 128160265 128163924 + CBR3 chr21 36135079 36146562 + CBX5 chr12 54230942 54280133 - CLASP1 chr2 121337776 121649587 - DBNDD1 chr16 90004871 90020128 - ECI1 chr16 2239402 2252300 - EIF4A1 chr17 7572706 7579006 + HNRNPA1P48 chr16 51553436 51647132 + HNRNPA3 chr2 177212563 177223958 + IGFBP2 chr2 216632828 216664436 + KANK1 chr9 470291 746106 + LCMT1 chr16 25111731 25178231 + MANEAL chr1 37793802 37801137 + MBNL1 chr3 152243828 152465780 + NIP7 chr16 69337996 69343106 + PRCP chr11 82822936 82970584 - RPS12 chr6 132814569 132817564 + RPS19 chr19 41860255 41872925 + SAP30L chr5 154445997 154461053 + SENP3-EIF4A1 chr17 7563287 7578715 + SLC44A2 chr19 10602457 10644557 + SYNRG chr17 37514807 37609472 - TBCEL chr11 121024072 121090775 + YTHDF2 chr1 28736621 28769775 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AL157935.2 chr9 127934503 127940952 + SNHG5 chr6 85650491 85678932 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.