exRNAdisease

Entry Detail

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General Information

Database ID: exR0429055 RNA Name: AK3 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 4709556 End Site(bp): 4742043 External Links: ENSG00000147853

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CD74 chr5 150400041 150412929 - BAZ2A chr12 56595596 56636816 - ERCC3 chr2 127257290 127294166 - MT-ATP6 chrMT 8527 9207 + RPLP0 chr12 120196699 120201235 - DYNC1H1 chr14 101964573 102056443 + TPRN chr9 137191617 137204193 - ATP1A1 chr1 116372668 116410261 + FNDC5 chr1 32862268 32872482 - BX255925.3 chr9 137217452 137219361 + CD9 chr12 6199715 6238271 + THOC6 chr16 3024027 3027755 + RAB7A chr3 128726183 128814798 + RPS3 chr11 75399515 75422280 + APTX chr9 32886601 33025130 - EIF5 chr14 103333544 103345025 + GAPDH chr12 6534512 6538374 + ZNF280D chr15 56630181 56734086 - BRK1 chr3 10115675 10127190 + FZD3 chr8 28494205 28574267 + FBXO38 chr5 148383935 148442836 + MTFR1L chr1 25818640 25832942 + RPS17 chr15 82536750 82540459 - RPL17 chr18 49488453 49492523 - ZNF8 chr19 58278955 58302791 + CHD4 chr12 6570082 6614524 - WDR11 chr10 120851305 120909524 + SELENOO chr22 50200979 50217616 + RPL32 chr3 12834485 12841582 - ACTG1 chr17 81509971 81523847 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand HOTAIRM1 chr7 27095647 27100265 + NBR2 chr17 43125551 43153671 + OIP5-AS1 chr15 41283990 41309737 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.