exRNAdisease

Entry Detail

---



General Information

Database ID: exR0429058 RNA Name: AK6 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 69350984 End Site(bp): 69370013 External Links: ENSG00000085231

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AL513165.2 chr9 37512547 37592469 - BICC1 chr10 58512872 58831435 + FBXO10 chr9 37510892 37576380 - FOXP4 chr6 41546426 41602384 + GLRX3 chr10 130136391 130184521 + KPNA1 chr3 122421902 122514945 - LTV1 chr6 143843338 143863812 + NFS1 chr20 35668052 35699355 - PPP2R1B chr11 111726908 111766389 - RAB12 chr18 8609437 8639382 + RAB1A chr2 65070696 65130331 - RANBP9 chr6 13621498 13711835 - RBMX chrX 136848004 136880764 - SNRPD2 chr19 45687454 45692569 - TAF9 chr5 69364743 69370013 - TJP1 chr15 29699367 29968865 - USP1 chr1 62436297 62451804 + WDFY4 chr10 48684876 48982956 + WDR7 chr18 56651343 57036606 + ZFAND5 chr9 72351413 72365235 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL138689.2 chr13 106491147 106521630 + IQCH-AS1 chr15 67290636 67521844 - SNHG3 chr1 28505980 28510892 + WDR7-OT1 chr18 57027832 57038845 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.